Preparation and Characterization of Liposomal Everolimus by Thin-Film Hydration Technique

Table 1

Experimental design for the optimization of liposomes’ lipid composition and lipid : drug ratio (concentration of everolimus was maintained at 0.06 mM).

Sample	Lipidic components	Lipid ratio PC : Chol	Lipid : drug molar ratio
Blank	POPC : Chol	9 : 1	-
A	POPC : Chol	9 : 1	60 : 1
B	POPC : Chol	9 : 1	45 : 1
C	POPC : Chol	9 : 1	30 : 1
D	POPC : Chol	7 : 3	60 : 1
E	DOPC : Chol	9 : 1	60 : 1