Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Compound code</td><td class="align_center">Acute inhalation toxicity</td><td class="align_center">Skin sensitization</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left"><b>7</b></td><td class="align_center">−</td><td class="align_center">−</td></tr><tr><td class="align_left"><b>8</b></td><td class="align_center">−</td><td class="align_center">−</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>“+” = toxic, “−” = nontoxic.<br/></div></td></tr></table>

<div>Acute inhalation toxicity and skin sensitization of compounds <b>7</b> and <b>8</b>.</div>

Advances in Pharmacological and Pharmaceutical Sciences

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Table 2

Table 2: Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives 

Table 2 | Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives 