Research Article
In Vitro Antibacterial, DPPH Radical Scavenging Activities, and In Silico Molecular Modeling of Isolated Compounds from the Roots of Clematis hirsuta
Table 4
Bacterial growth inhibition zone of extracts and isolated compounds.
| Test sample | Concentration (mg/mL) | Inhibition zone in mm (mean ± SD) | S. aureus | S. pyogenes | E. coli | P. aeruginosa |
| MeOH extract | 100 | 8.20 ± 0.12 | 12.30 ± 0.21 | 9.20 ± 0.12 | 9.30 ± 0.22 | 50 | NI | 8.20 ± 0.12 | 7.20 ± 0.12 | NI |
| n-hexane: EtOAc (1 : 1) extract | 100 | 11.20 ± 0.13 | 10.30 ± 0.25 | 8.40 ± 0.26 | 15.20 ± 0.17 | 50 | 7.10 ± 0.13 | 8.30 ± 0.13 | NI | 10.20 ± 0.12 |
| 3 | 5 | 11.10 ± 0.17 | 10.50 ± 0.21 | 10.30 ± 0.24 | 10.60 ± 0.55 | 2.5 | 7.27 ± 0.55 | 8.70 ± 0.22 | 8.20 ± 0.17 | 8.20 ± 0.17 |
| 5 | 5 | 9.07 ± 0.12 | 8.80 ± 0.17 | 9.10 ± 0.19 | 9.10 ± 0.12 | 2.5 | NI | NI | 7.60 ± 0.13 | NI |
| 6 | 5 | 10.10 ± 0.10 | 10.20 ± 0.17 | 10.40 ± 0.29 | 10.20 ± 0.22 | 2.5 | 8.27 ± 0.46 | 7.50 ± 0.22 | 8.30 ± 0.16 | 8.40 ± 0.24 |
| Ciprofloxacin | 0.5 | 18.42 ± 0.26 | 19.93 ± 0.21 | 20.00 ± 0.21 | 22.18 ± 0.22 |
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Note. NI: no inhibition.
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