Advances in Pharmacological and Pharmaceutical Sciences

Research Article

Changes in IL-2 and IL-10 during Chronic Administration of Isoniazid, Nevirapine, and Paracetamol in Rats

Table 2

Average (mean ± SD) full blood count and platelets during treatment of the rats with NVP, INH, and PAR over the study period.
GroupRCC (×1012/l)Hb (g/dl)Hct (l/l)MCV (fl)MCH (pg)MCHC (g/dl)Plt (×109/l)WCC (×109/l)Neu (×109/l)Ly (×109/l)Mo (×109/l)Eos (×109/l) Bas (×109/l)
Untreated             
0 days
S             
2 days
7 days
14 days
28 days
42 days
NVP             
2 days
7 days
14 days
28 days
42 days
INH             
2 days
7 days
14 days
28 days
42 days
PAR             
2 days
7 days
14 days
28 days
42 days
RCC: red cell count; Hb: haemoglobin; Hct: haematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration; Plt: platelets; WCC: white cell count; Neu: neutrophils; Ly: lymphocytes; Mo: monocytes; Eos: eosinophils; Bas: basophils, S: saline; INH: isoniazid; NVP: nevirapine; PAR: paracetamol; .