Research Article
QSAR Study of (5-Nitroheteroaryl-1,3,4-Thiadiazole-2-yl) Piperazinyl Derivatives to Predict New Similar Compounds as Antileishmanial Agents
Table 3
Correlation matrix between different obtained descriptors.
| Variables | pIC50 | | | | | | | MW | MV | MR | n | D | Pc |
| pIC50 | 1 | | | | | | | | | | | | | | -0.167 | 1 | | | | | | | | | | | | | -0.424 | 0.381 | 1 | | | | | | | | | | | | 0.222 | 0.160 | 0.456 | 1 | | | | | | | | | | | -0.159 | 0.181 | 0.707 | 0.292 | 1 | | | | | | | | | | 0.616 | -0.320 | -0.817 | 0.142 | -0.597 | 1 | | | | | | | | | 0.416 | -0.227 | -0.163 | 0.155 | -0.011 | 0.282 | 1 | | | | | | | MW | -0.033 | -0.446 | 0.249 | 0.099 | 0.379 | -0.213 | 0.364 | 1 | | | | | | MV | -0.022 | 0.135 | 0.384 | 0.167 | 0.455 | -0.318 | 0.354 | 0.695 | 1 | | | | | MR | -0.168 | 0.149 | 0.612 | 0.256 | 0.582 | -0.515 | 0.313 | 0.796 | 0.837 | 1 | | | | n | -0.229 | 0.006 | 0.372 | 0.169 | 0.194 | -0.304 | -0.066 | 0.153 | -0.323 | 0.247 | 1 | | | D | 0.014 | -0.680 | -0.233 | -0.086 | -0.193 | 0.203 | -0.057 | 0.176 | -0.584 | -0.240 | 0.629 | 1 | | Pc | 0.185 | -0.608 | -0.677 | -0.281 | -0.523 | 0.571 | -0.098 | -0.290 | -0.756 | -0.722 | 0.099 | 0.707 | 1 |
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