Research Article

Multiple Venous Thromboembolism Pharmacologic Agents Are Associated with an Increased Risk for Early Postoperative Complications following a Total Joint Arthroplasty

Table 2

Demographics of patients on 2 or more VTE medications postoperatively.

ParameterTest value2 or more inpatient prophylaxis (N = 881)Others (N = 1779)

Body mass indexT-test0.12231.6 (6.5)32.1 (6.7)
Rank sum0.10030.8 (27.1–35.5)31.2 (27.4–36.4)

Case jointChi-square0.165TKA = 537TKA = 1135
THA = 344THA = 644

SideChi-square0.987Left = 408Left = 821
Right = 455Right = 923
Both = 18Both = 35

RaceChi-square0.996Caucasian = 732Caucasian = 1476
AA = 111AA = 226
Unknown = 38Unknown = 76

GenderChi-square0.143Male = 374Male = 701
Female = 507Female = 1078

AgeT-test<0.00168.6 (10.1)64.7 (10.4)
Rank sum<0.00169.0 (62.0–76.0)65.0 (58.0–72.0)

Preoperative ASA (categorical)Chi-square<0.0011 = 31 = 17
2 = 1562 = 489
3 = 6253 = 1165
4 = 964 = 107

Preoperative ASA (continuous)T-test<0.0012.9 (0.5)2.8 (0.6)
Rank sum<0.0013.0 (3.0–3.0)3.0 (2.0–3.0)

AA: African American; ASA: American Society of Anesthesiologists; THA: total hip arthroplasty; TKA: total knee arthroplasty; VTE: venous thromboembolism. Patients on 2 or more VTE medications postoperatively were more likely to be older and have a higher preoperative ASA score.