Anemia

Anemia / 2019 / Article / Tab 2

Research Article

A Comparative Study of Interleukin 6, Inflammatory Markers, Ferritin, and Hematological Profile in Rheumatoid Arthritis Patients with Anemia of Chronic Disease and Iron Deficiency Anemia

Table 2

Comparative analysis of immunological and hematological marker indices in patients with IDA, RA-ACD, and RA-COMBI and healthy control group.

ParameterIDARA-ACDRA-COMBIControlP≤1 vs 21 vs 31 vs 43 vs 43 vs 22 vs 4

No. patientsN=30N=23N=20N=50
Sex, F/M23/717/620/046/4-- - - ---
Age (years)43±7.3242.56±11.0637.55±9.9538.78±7.47NSNSNSNSNSNSNS
Rang(25-60)(24-60)(24-55)(25-55)
WBC(/μ)6.36±2.708.67±4.084.76±2.505.5±2.60.0010.0030.001NS0.0010.0010.001
RBC(/μL)4.4±0.693.25±0.604.49±0.994.88±0.40.0010.001NS0.002NS0.0010.001
HGB (g/dl)8.53±1.019.15±1.379.79±1.1613.21±1.280.001NS0.0010.0010.001NS0.001
HCT (%)27.86±2.3928.46±4.9631.54±9.5141.41±3.830.001NS0.010.0010.001NS0.001
MCV(fl)64.4±8.9585±6.2474.7±4.887.64± 5.70.0010.0010.0010.0010.0010.0010.001
MCH (pg)19.8±3.9528.6±4.7623.5±2.3727.12±2.340.0010.0010.0010.0010.0010.0010.001
MCHC gl/dl30.61±2.5831.77±5.2631.51±1.8431.87±1.17NSNSNSNSNSNSNS
ESR (mm/h)6.1±1.272.56±30.563.5±36.97.98±3.70.0010.008NS0.0010.001NS0.001
hsCRP (mg/L)1.26±0.967.09± 2.37.18±2.60.96±0.110.0010.0010.001NS0.001NS0.001
Anti-CCP (U/ml)2.41±1.32258.6±43.5324.3±63.32.4±1.40.0010.0010.001NS0.001NS0.001
IL-6 (pg/ml)2.18±1.4431.3±52.2459±61.84.94± 2.40.0010.0010.001NS0.001NS0.001
ferritin(ng/ml)7.17±1.0083.39±22.98.38±1.3156.5±30.70.00010.001NS0.0010.0010.0010.001

P is statistically significant among the groups at level< 0.05. Data are reported as mean ± standard deviation (range).
Multiple comparisons among 4 groups depended on LSD.
IDA: iron deficiency anemia; RA-ACD: anemia of chronic disease; RA-COMBI: combination of IDA and ACD. F: female; M: male.

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