A Monocentric Retrospective Study about the Correlation between Histology and Cytology of Thyroid Indeterminate Nodules Classified as TIR 3A and TIR 3B, according to 2014 Italian Consensus for Classification and Reporting of Thyroid Cytology

Table 1

Diagnostic categories, expected risk of malignancy, and suggested management in 2014 ICCRTC classification [14].

	Diagnostic category	Expected rate of malignancy (%)	Recommendation
TIR1	Not diagnostic	Undefined	FNA repetition after at least one month
TIR1C	Not diagnostic, cystic	Low, based on clinical features	Focused on clinical features and/or FNA repetition
TIR2	Not malignant/benign	<3	Follow-up
TIR3A	Indeterminate nodule with low risk of malignancy	<10	Follow-up/FNA repetition
TIR3B	Indeterminate nodule with high risk of malignancy	15–30	Surgery
TIR4	Suspicious of malignancy	60–80	Surgery/intraoperatory histology eventually
TIR5	Malignant	95	Surgery; further diagnostic exams if necessary