Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia

Figure 4

(a) Pre therapy immunohistological section of bone marrow biopsy stained for CD34 (400x magnification) showing microvessels with or without lumen which are stained in brown (mean MVD = 24). (b) Post therapy immunohistological section of bone marrow biopsy of same patient showing reduced number of microvessels (mean MVD = 3.44).

(a)

(b)