Review Article

[Retracted] Plasmablastic Lymphoma: A Review of Current Knowledge and Future Directions

Table 1

The main differential diagnosis of PBL.

Clinical presentationFrequently oral cavityOften extranodal (jaws and orbits)Wide variety of presentationsInvolves body cavityWide variety of presentationsBM (extramedullary in plasmacytoma)BM (extramedullary in plasmacytoma)

Immunocompetency+/−++++++/−+++++

Association with HIV++++++++++

Association with HHV8+/− (usually −)+

LCA+/−+++/−+/−+/−+/−

B-cell markers
 CD20+++/−
 CD79a +/− (usually −)+++/− (usually −)+/− (usually −)

CD138++++
CD56+/− (usually −)Rare +Rare +Rare ++/−Usually +Usually +

Ki67High >70%High
>90%
High
<90%
High
>80%
High
>80%
LowHigh
>70%

OtherBLIMP1+CD10
+
BCL-6
Usually +
CD30
Usually +
ALK+Serum M-spike CRABSerum M-spike
CRAB

CRAB: hypercalcemia, kidney disease, anemia, and bone lytic lesions [67].