Research Article
Interference of Antinuclear Antibody (ANA) in Indirect Immunofluorescence Assay (IIFA)-Based Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA) Interpretation
Table 2
ANA-IIFA pattern results versus pANCA positivity.
| Sr no | ANA-IIFA pattern | No of cases | Positive pANCA (%) | Cohen's kappa | -Value (at significant level <0.05) |
| 01 | Nuclear homogenous (AC1) | 89 | 28 (31.5) | | 0.00001 | 02 | Speckled (AC4/AC5) | 81 | 9 (11.1) | | 0.293 | 03 | Centromere (AC3) | 45 | 3 (6.7) | | 0.101 | 04 | Mitosis positive (spindle/centrosome) (AC24/AC25) | 73 | 2 (2.7) | | 0.001 | 05 | Dense fine speckled (DFS) 70 (AC2) | 29 | 3 (10.3) | | 0.372 | 06 | All positive | 307 | 45 (14.7) | 0.822 | 0.007 |
|
|