Research Article
Autoimmune Mechanisms of Interferon Hypersensitivity and Neurodegenerative Diseases: Down Syndrome
Table 1
Candidate down syndrome neuropathology genes on Ch21.
| Gene | Function |
| RCAN1 | Regulator of calcineurin 1 | MAFD3 | Major affective disorder 3 | JAM4 | Junctional adhesion molecule 4 | ADARB1 | Adenosine deaminase, RNA specific, B1 | DOPEY2 | Dopey family member 2 | mir155 | micro-RNA 155 | NCAM | Nuclear receptor interacting protein | DYRK | Dual specificity tyrosine-(y)-phosphorylation regulated kinase 1A | MX1 | Myxovirus (influenza) resistance-1 | SIM2 | Single-minded homolog2 (drosophila) | SYNJ1 | Synaptojanin 1 | DIP2a | Disco interacting protein | PCP4 | Purkinje cell protein 4 | CD18 | Integrein beta 2 | SOD1 and SOD2 | Superoxide dismutase |
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