Review Article

Role of Autoimmune Responses in Periodontal Disease

Table 1


HumoralCellular

( ) Antibody to aggregated IgG (rheumatoid factor) detected in gingiva and saliva( ) Lymphocytotoxicity shown for oral epithelial cells
( ) Antibody levels to double stranded DNA were elevated in dog gingival( ) Histological damage observed in gingival human fibroblasts with associated mononuclear cells
( ) Elevated levels of serum antibody to human collagen type I( ) Lymphocytotoxic killing of autologous fibroblasts with associated mononuclear cells
( ) IgM, IgA rheumatoid factor antibody to human collagen types I and III produced by mononuclear cells( ) Lymphoblastogenesis detected to native and denatured collagen
( ) Serum IgG antibodies to native and denatured types I and III bovine collagen detected in juvenile periodontitis( ) Cellular immunity to proteoglycan detected in periodontal disease patients