The Role of Decay Accelerating Factor in Environmentally Induced and Idiopathic Systemic Autoimmune Disease

Figure 3

CD4⁺ T-cell expansion in mHgIA-resistant DBA/2 consists of CD25 negative cells. NZB and DBA/2 mice were exposed to PBS (white bar) or HgCl₂ (black bar) for 5 weeks. Splenocytes were then cultured in the presence of PMA/ionomycin and analyzed for percent CD4⁺ T cells (a) and CD4⁺CD25⁻ T cells (b). Percentages represent cells in total spleen cells. 𝑛=4/group.

(a)

(b)