Anti-Transglutaminase 6 Antibodies in Children and Young Adults with Cerebral Palsy
Table 1
(a) Clinical data of children with cerebral palsy and autoantibodies to TG6. (b) Summary of gastrointestinal data and laboratory results previously performed [6, 10] for those CP children testing positive for autoantibodies to TG6.
(a)
Patients sex/age (—/yr)
IQ N = normal MR = mental retardation
Diagnosis/subdiagnosis of CP
GMFCS
CP etiology
Neonatal data W = gestational age when born
Brain MRI/CT/US
Epilepsy and treatment
F/17
N
AU/ A
I
Unknown
PN
MRI, normal
—
M/18
MR
TP
V
Asphyxia
PN Asphyxia at birth
US, wide ventricles, small subependymal bleeding
—
M/4
MR
TP
IV-V
Traumatic injury 3 months of age
PN
CT, focal infarct, cortical, subcortical, and basal ganglia damage
Lamotrigine
M/12
N
A
II
Hydrops fetalis
Hydrops fetalis CS; W 28
MRI, cortical and subcortical damage
—
F/18
MR
TP
V
Asphyxia
CS; W 40
CT, focal infarct
—
F/18
N
HF/HP
II
Left cerebral infarction at 1 years of age
PN
MRI and CT, cortical and subcortical damage, and hydrocephalus