Immunotherapy of Neuromyelitis Optica

Figure 1

Summary of the mechanisms of action of immunotherapies in NMO. Abbreviations: B=B cell, C5=protein 5 of complement, CX=cytotoxic agent, IL=interleukin, IS=immunosuppressant, IVIG=intravenous immunoglobulin, PL=plasmacell, PMN=polymorphonuclear cell, Th=T helper cell.