DNA Damage in Rheumatoid Arthritis: An Age-Dependent Increase in the Lipid Peroxidation-Derived DNA Adduct, Heptanone-Etheno-2′-Deoxycytidine
Figure 2
8-oxo-dG and εdA levels in blood cells from RA patients and controls show no differences. (a) The respective median (range) values of 8-oxo-dG from RA patients and controls were 176.4 (52.5–449) and 127.1 (58.1–372) per 109 bases. The straight and dotted lines represent linear approximation of the values of 8-oxo-dG versus age from RA patients and controls. (b) The respective median (range) values of εdA from RA patients and controls were 29 (2.6–1635) and 34.7 (0.2–121) per 109 bases. The straight and dotted lines represent linear approximation of the values of εdA versus age from RA patients and controls.
