Review Article
Heterogeneity in Multiple Sclerosis: Scratching the Surface of a Complex Disease
Table 1
Classic MS and its variants.
| Classic MS | MS variants |
| (i) Relapsing-remitting (RRMS): 85% of all MS cases at onset | (i) Neuromyelitis Optica (NMO) | (ii) Second ary progressive (SPMS): 70%–80% of RRMS cases after 10 years from disease onset | (ii) Balo’s concentric sclerosis | (iii) Primary progressive (PPMS): 15% of all MS cases at onset | (iii) Margburg’s MS variant | (iv) Progressive-relapsing (PRMS): very small percentage | (iv) Schilder’s MS variant |
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