Research Article
Fetal and Postnatal Nicotine Exposure Modifies Maturation of Gonocytes to Spermatogonia in Mice
Table 2
Evaluated parameters (median and interquartile ranges) in control and nicotine-exposed animals.
| Age (dpp) | Number of G in contact with BM/1000 μm2 | Number of G without contact with BM/1000 μm2 | Number of spermatogonia/1000 μm2 | Number of cells in proliferation/1000 μm2 | Control | Nicotine | Control | Nicotine | Control | Nicotine | Control | Nicotine |
| 3 | 0.978 0.363-2.254 | 0.534 0.273-1.352 | 0.416 0.343-1.156 | 0.654 0.307-1.515 | | | 10.380 6.817-14.000 | 6.072 2.539-9.539 |
| 7 | 1.645 0.708-3.606 | 0.859 0.328-1.926 | 0.010 0.010-0.343 | 0.409 0.353-0.873 | 0.144 0.123-0.364 | 0.108 0.088-0.140 | 1.1228 0.324-1.868 | 1.074 0.726-1.7462 |
| 10 | | | 0.010 0.010-0.612 | 0.199 0.124-0.406 | 1.291 1.003-1.665 | 1.066 0.398-1.701 | 5.122 1.396-8.267 | 3.162 0.317-8.605 |
| 16 | | | | | 1.712 0.937-3.210 | 1.378 1.005-1.761 | 2.114 1.965-2.787 | 1.784 1.093-2.290 |
| 35 | | | | | 0.912 0.524-1.489 | 0.517 0.216-0.892 | 6.809 5.157-9.583 | 5.040 3.102-7.630 |
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control vs. nicotine of the same age. G = gonocyte; BM = basement membrane. |