Effect of Lidocaine and Epinephrine on Human Erythrocyte Shape and Vesiculability of Blood Cells

Table 1

Number of events within the chosen flow cytometer SSC-A/FSC-A region corresponding to platelets and EVs (Figure 1) in the isolate from blood treated with L/E.

	Subject 1; (1/L)	Subject 2; (1/L)	Subject 3; (1/L)	Average; (1/L)
Control; (added PBS)	2602	3325	2065	2664
Test; (added L/E)	9290	9236	8670	9065

SSC-A/FSC-A: side scattered light/forward scattered light; EVs: extracellular vesicles; PBS: citrated and phosphate-buffered saline; L/E: lidocaine/epinephrine. Blood was donated by three authors with no record of disease and was processed immediately after the addition of L/E. The region contained more than 90% of events in all density plots.