Computational Analysis Reveals the Association of Threonine 118 Methionine Mutation in PMP22 Resulting in CMT-1A

Table 2

The disease associated SNPs are predicted from PHDsnp and SNP&GO.

SNP ID	Mutations	PHDsnp		SNP&GO
		RI score	Effect	Score	Effect
rs28936682	R157W	8	Disease	8	Disease
rs104894617	L16P	6	Disease	6	Disease
rs104894618	S79C	6	Disease	0	Neutral
rs104894619	T118M	7	Disease	6	Disease
rs104894620	M69K	9	Disease	8	Disease
rs104894622	H12Q	6	Disease	7	Disease
rs104894624	G150C	6	Disease	8	Disease
rs104894625	S22F	6	Disease	7	Disease
rs104894626	W28R	9	Disease	9	Disease
rs104894627	D37V	9	Disease	8	Disease
rs375449671	Y136S	7	Disease	8	Disease